Immunoglobulin A antibody against hepatitis B core antigen in the acute and persistent infection with hepatitis B virus.

@article{Nomura1985ImmunoglobulinAA,
  title={Immunoglobulin A antibody against hepatitis B core antigen in the acute and persistent infection with hepatitis B virus.},
  author={Masayasu Nomura and Mitsunobu Imai and Fumio Tsuda and Seiichi Furuta and Yoshihiro Akahane and Kuniomi Tachibana and Sadakazu Usuda and Yuzo Miyakawa and Makoto Mayumi},
  journal={Gastroenterology},
  year={1985},
  volume={89 5},
  pages={1109-13}
}
Antibody to hepatitis B core antigen of immunoglobulin A class was determined in the serum of patients infected with hepatitis B virus by a sandwich-type solid-phase radioimmunoassay with monoclonal antibodies. The antibody, as defined by a sample to normal ratio greater than 2.1, was detected in all of 39 patients with acute hepatitis, with titers varying widely depending on the time of blood sampling. In persons with persistent infection, the antibody was detected in only 2 (4%) of 46… CONTINUE READING