Immunogenomic analysis of insect bite hypersensitivity in a model horse population.

  title={Immunogenomic analysis of insect bite hypersensitivity in a model horse population.},
  author={Leona Vychodilova and J{\'a}n Matia{\vs}ovic and O. V. Bobrova and J{\'a}n Futas and Marie Klumplerova and Karla Stejskalova and Michaela Cvanov{\'a} and Eva J{\'a}nov{\'a} and Jarmila Osickova and Mirko Vysko{\vc}il and Mark{\'e}ta Sedlinsk{\'a} and Ladislav Du{\vs}ek and Eliane Marti and Petr Horin},
  journal={Veterinary immunology and immunopathology},
  volume={152 3-4},
Equine insect bite hypersensitivity (IBH) is a seasonal IgE-mediated dermatosis caused by bites of insects of the genus Culicoides. A familial predisposition for the disease has been shown but, except for the MHC, the genes involved have not been identified so far. An immunogenomic analysis of IBH was performed in a model population of Old Kladruby horses, all living in the same environment. Clinical signs of IBH were used as phenotypic manifestation of IBH. Furthermore, total serum IgE levels… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS