Immunogenicity of various presentation forms of PorA outer membrane protein of Neisseria meningitidis in mice.

@article{Peeters1999ImmunogenicityOV,
  title={Immunogenicity of various presentation forms of PorA outer membrane protein of Neisseria meningitidis in mice.},
  author={C C Peeters and I J Claassen and Marion Schuller and Gideon Kersten and E M van der Voort and Jan T. Poolman},
  journal={Vaccine},
  year={1999},
  volume={17 20-21},
  pages={
          2702-12
        }
}
In this study we compare different vaccine formulations containing meningococcal PorA outer membrane protein; purified PorA, outer membrane vesicles (OMV) and immune-stimulating complexes (iscom). Bactericidal antibodies could be generated by the OMV and iscom formulation but not with purified PorA using either A1PO4 or Quil-A as adjuvant. OMV and iscom formulations revealed similar immunogenicity when tested in a dose response manner, with respect to bactericidal as well as OMV-binding… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 22 CITATIONS

Determination of bactericidal activity of serum against Vibrio cholerae outer membrane vesicles in BALB/c mice

M Sedaghat, Seyed Davar Siadat, +3 authors Fereshteh Shahcheraghi
  • 2018
VIEW 1 EXCERPT