Immunogenicity of recombinant GP5 protein of porcine reproductive and respiratory syndrome virus expressed in tobacco plant.

@article{Chia2010ImmunogenicityOR,
  title={Immunogenicity of recombinant GP5 protein of porcine reproductive and respiratory syndrome virus expressed in tobacco plant.},
  author={M Chia and S Hsiao and Hui-Ting Chan and Yi-Yin Do and Pung-Ling Huang and Hui-Wen Chang and Yi-Chieh Tsai and Chun-Ming Lin and Victor Pang and Chian-Ren Jeng},
  journal={Veterinary immunology and immunopathology},
  year={2010},
  volume={135 3-4},
  pages={234-42}
}
The aim of the study was to evaluate the immunogenicity of the ORF5-encoded major envelop glycoprotein 5 (GP5) of porcine reproductive and respiratory syndrome virus (PRRSV) expressed in tobacco plant as a potential pig oral vaccine in protection against PRRSV infection. Six-week-old PRRSV-free pigs were fed four times orally with 50g of chopped fresh GP5 transgenic tobacco leaves (GP5-T) (GP5 reaching 0.011% of total soluble protein) or wild-type tobacco leaves (W-T) each on days 0, 14, 28… CONTINUE READING
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