Immunogenicity of poly-D-lysine, a potential polymeric drug carrier

@inproceedings{Vermeersch1994ImmunogenicityOP,
  title={Immunogenicity of poly-D-lysine, a potential polymeric drug carrier},
  author={Hubert Vermeersch and Jean Paul Remon},
  year={1994}
}
Abstract The antibody response against poly-D-lysine, a potential polymeric drug carrier, was evaluated in rabbits. Intradermal injection of poly-D-lysine in rabbits induced the formation of antibodies. After the first injection, IgG and IgM were formed whereas after the subsequent injections only IgG was detected. A booster effect was seen after the second injection. The antibodies were stereospecific since they did not cross-react with poly-L-lysine. Two hypotheses for the deviating… CONTINUE READING

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