Immunogenicity of a 2-dose priming and booster vaccination with the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine.

@article{Silfverdal2009ImmunogenicityOA,
  title={Immunogenicity of a 2-dose priming and booster vaccination with the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine.},
  author={Sven Arne Silfverdal and Birthe Hogh and Marianne Adeleide Riise Bergsaker and Helena Skerlikova and Patricia Lommel and D Bileka Borys and Lode M Schuerman},
  journal={The Pediatric infectious disease journal},
  year={2009},
  volume={28 10},
  pages={
          e276-82
        }
}
BACKGROUND The immunogenicity of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) was determined following a simplified 2-dose priming and the more commonly employed 3-dose priming both followed by a booster dose. METHODS A total of 351 healthy subjects were primed with PHiD-CV at either 3 and 5 or 3, 4 and 5 months of age followed in all subjects by a booster dose at 11 to 12 months of age. Serotype-specific pneumococcal responses were… CONTINUE READING
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