Immunogenicity of Streptococcus pneumoniae type 14 capsular polysaccharide: influence of carriers and adjuvants on isotype distribution.

Abstract

This project investigated the effects of novel carriers and adjuvants on the isotype of murine immunoglobulin G (IgG) antibody to pneumococcal capsular polysaccharide type 14 (S14PS). S14PS conjugated to bovine serum albumin induced a weak antibody response which was 100% IgG1 following injection without adjuvant. The same polysaccharide conjugated to… (More)

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Cite this paper

@article{Wijgert1991ImmunogenicityOS, title={Immunogenicity of Streptococcus pneumoniae type 14 capsular polysaccharide: influence of carriers and adjuvants on isotype distribution.}, author={Janneke H H M van de Wijgert and Andr{\'e} F. M. Verheul and Helena Snippe and Irene J. Check and Roger Hunter}, journal={Infection and immunity}, year={1991}, volume={59 8}, pages={2750-7} }