Immunogenicity of HSP-70, KMP-11 and PFR-2 leishmanial antigens in the experimental model of canine visceral leishmaniasis.

@article{Carrillo2008ImmunogenicityOH,
  title={Immunogenicity of HSP-70, KMP-11 and PFR-2 leishmanial antigens in the experimental model of canine visceral leishmaniasis.},
  author={Eugenia Carrillo and Mart{\'i}n Crusat and Javier Nieto and C. Chicharro and Mar{\'i}a del Carmen Thomas and Enrique Redondo Mart{\'i}nez and Basilio Valladares and Carmen Ca{\~n}avate and Jose M Requena and Manuel Carlos L{\'o}pez and Jorge Alvar and Javier Moreno},
  journal={Vaccine},
  year={2008},
  volume={26 15},
  pages={1902-11}
}
Zoonotic visceral leishmaniasis (ZVL) is a parasitic disease caused by Leishmania infantum/L. chagasi that is emerging as an important medical and veterinary problem. Dogs are the domestic reservoir for this parasite and, therefore, the main target for controlling the transmission to humans. In the present work, we have evaluated the immunogenicity of the Leishmania infantum heat shock protein (HSP)-70, paraflagellar rod protein (PFR)-2 and kinetoplastida membrane protein (KMP)-11 recombinant… CONTINUE READING
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