Immunogenicity evaluation of a lipidic amino acid-based synthetic peptide vaccine for Chlamydia trachomatis.

@article{Zhong1993ImmunogenicityEO,
  title={Immunogenicity evaluation of a lipidic amino acid-based synthetic peptide vaccine for Chlamydia trachomatis.},
  author={Guangming Zhong and Istvan Toth and Ronald E Reid and Robert C. Brunham},
  journal={Journal of immunology},
  year={1993},
  volume={151 7},
  pages={3728-36}
}
Lipidic amino acid-based synthetic peptides derived from the variable domains (VD) of Chlamydia trachomatis outer membrane protein 1 were evaluated as potential candidate sequences in a vaccine. A peptide sequence designated P2 from the VD IV of serovar B contained a B cell epitope capable of eliciting antibodies binding to serovar B elementary bodies (EB) and a T helper site capable of presentation by multiple H-2 alleles. Polymerization of the P2 into polylysine to form lipid core peptides… CONTINUE READING

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