Immunogenicity and toxicity of transferrin receptor-targeted hybrid peptide as a potent anticancer agent


Transferrin receptor (TfR) is a cell membrane-associated glycoprotein involved in the cellular uptake of iron and the regulation of cell growth. Recent studies have shown elevated expression levels of TfR on cancer cells compared with normal cells. We previously designed a TfR-lytic hybrid peptide, which combines the TfR-binding peptide and a lytic peptide… (More)
DOI: 10.1007/s00280-013-2074-4


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