Immunogenicity and safety of hepatitis A vaccine in children with chronic liver disease.

@article{Ferreira2003ImmunogenicityAS,
  title={Immunogenicity and safety of hepatitis A vaccine in children with chronic liver disease.},
  author={Cristina Helena Targa Ferreira and Themis Reverbel da Silveira and Sandra Vieira and Adriano N R Taniguchi and Jorge Escobar Pereira-Lima},
  journal={Journal of pediatric gastroenterology and nutrition},
  year={2003},
  volume={37 3},
  pages={258-61}
}
BACKGROUND Acute hepatitis A superimposed on chronic liver disease has been associated with a more severe course of disease and development of fulminant hepatitis. The aim of this study was to evaluate the immunogenicity and safety of an inactivated hepatitis A virus vaccine in children with chronic liver disease. PATIENTS AND METHODS This was an open, prospective, and controlled trial with 89 anti-HAV negative children between 1 and 16 years of age studied at a pediatric liver disease and… CONTINUE READING