Immunogenicity and safety of a 13-valent pneumococcal conjugate vaccine in healthy infants in Japan.

@article{Togashi2013ImmunogenicityAS,
  title={Immunogenicity and safety of a 13-valent pneumococcal conjugate vaccine in healthy infants in Japan.},
  author={Takehiro Togashi and Masako Yamaji and Allison R Thompson and Peter C. Giardina and Masakazu Aizawa and Scott Patterson and William C. Gruber and Daniel A. Scott},
  journal={The Pediatric infectious disease journal},
  year={2013},
  volume={32 9},
  pages={
          984-9
        }
}
BACKGROUND A 13-valent pneumococcal conjugate vaccine (PCV13) containing 6 additional serotypes not included in the 7-valent PCV has been developed to broaden protection against Streptococcus pneumoniae, which is responsible for over 500,000 deaths annually worldwide in children <5 years of age. This study in Japanese infants evaluated the immunogenicity and safety of PCV13 given subcutaneously, the standard route for infant vaccination in Japan. METHODS This phase 3, single-arm, open-label… CONTINUE READING
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