Immunogenicity and protective efficacy of the WI-1 adhesin of Blastomyces dermatitidis.

Abstract

People infected with Blastomyces dermatitidis develop strong immunity to the yeast surface adhesin WI-1, including antibody responses to the adhesive domain, a 25-amino-acid repeat, and cellular responses to the N terminus. We studied the immunogenicity of WI-1 and the ability of anti-WI-1 immune responses to protect against lethal pulmonary infection in… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.