Immunogenicity after one, two or three doses and impact on the antibody response to coadministered antigens of a nonavalent pneumococcal conjugate vaccine in infants of Soweto, South Africa.

@article{Huebner2002ImmunogenicityAO,
  title={Immunogenicity after one, two or three doses and impact on the antibody response to coadministered antigens of a nonavalent pneumococcal conjugate vaccine in infants of Soweto, South Africa.},
  author={Robin E. Huebner and Nontombi Marylucy Mbelle and B. M. Forrest and Dace V Madore and Keith P. Klugman},
  journal={The Pediatric infectious disease journal},
  year={2002},
  volume={21 11},
  pages={1004-7}
}
BACKGROUND Children <6 months of age are at increased risk of pneumococcal disease. The early immunogenicity of conjugate vaccines therefore may be important to prevent disease in young children. OBJECTIVES To determine the immunogenicity of a nonavalent pneumococcal conjugate vaccine after one dose, two doses and three doses and its impact on the antibody response to coadministered antigens. METHODS A total of 500 infants from Soweto were immunized at 6, 10 and 14 weeks of age with either… CONTINUE READING

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