Immunogenetics of systemic sclerosis.

@article{Dieud2011ImmunogeneticsOS,
  title={Immunogenetics of systemic sclerosis.},
  author={Philippe Dieud{\'e} and Catherine Boileau and Yannick Allanore},
  journal={Autoimmunity reviews},
  year={2011},
  volume={10 5},
  pages={
          282-90
        }
}
In the field of genetics of SSc, we are currently reaching a period of rapid data production. Several themes are already rising from the first wave of results. First, some genetic variants clearly predispose to multiple autoimmune diseases, thus providing evidence for a shared autoimmune genetic background. Second, multiple genes are involved in the SSc predisposition and as expected the genetic associations are quite modest. Third, unless for a small number of exceptions, the causative genetic… CONTINUE READING
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