Immunogenetic risk and protective factors for juvenile dermatomyositis in Caucasians.

@article{Mamyrova2006ImmunogeneticRA,
  title={Immunogenetic risk and protective factors for juvenile dermatomyositis in Caucasians.},
  author={Gulnara Mamyrova and Terrance P. O'Hanlon and Jason B Monroe and Danielle Mercatante Carrick and James D. Malley and Sharon Kay Adams and Ann Marie Reed and Ejaz A. Shamim and Laura A James-Newton and Frederick W Miller and LisaG. Rider},
  journal={Arthritis and rheumatism},
  year={2006},
  volume={54 12},
  pages={
          3979-87
        }
}
OBJECTIVE To define the relative importance (RI) of class II major histocompatibility complex (MHC) alleles and peptide binding motifs as risk or protective factors for juvenile dermatomyositis (DM), and to compare these with HLA associations in adult DM. METHODS DRB1 and DQA1 typing was performed in 142 Caucasian patients with juvenile DM, and the results were compared with HLA typing data from 193 patients with adult DM and 797 race-matched controls. Random Forests classification and… CONTINUE READING
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