Immunogenetic aspects of clinical and experimental uveitis.

  title={Immunogenetic aspects of clinical and experimental uveitis.},
  author={Rachel R Caspi},
  journal={Regional immunology},
  volume={4 5},
Genetic association of some immune-mediated human uveitic diseases with histocompatibility antigens, ethnic origin, familial background, or gender have suggested the presence a hereditary component in susceptibility. Experimental autoimmune uveoretinitis (EAU) can be induced in inbred rodents by immunization with evolutionarily conserved retinal proteins, and mimics many features of human uveitis. Susceptibility to EAU is genetically controlled, and the model is being used to study mechanisms… CONTINUE READING
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