Immunofluorescent studies of human chromosomes with antibodies against phosphorylated H1 histone

@article{Boggs2000ImmunofluorescentSO,
  title={Immunofluorescent studies of human chromosomes with antibodies against phosphorylated H1 histone},
  author={Barbara A. Boggs and C David Allis and A. Craig Chinault},
  journal={Chromosoma},
  year={2000},
  volume={108},
  pages={485-490}
}
Abstract.One of the prominent cell cycle-related modifications of histone proteins whose function remains unresolved is the phosphorylation of linker histone H1. In this work we have used indirect immunofluorescence on human cells with antibodies that are specific for phosphorylated histone H1 to examine the cellular distribution and chromosome association patterns of this protein. With confocal microscopy on whole cells, strong immunofluorescence was seen in association with mitotic… CONTINUE READING

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