Immunofluorescent localization of three Na,K-ATPase isozymes in the rat central nervous system: both neurons and glia can express more than one Na,K-ATPase.

@article{McGrail1991ImmunofluorescentLO,
  title={Immunofluorescent localization of three Na,K-ATPase isozymes in the rat central nervous system: both neurons and glia can express more than one Na,K-ATPase.},
  author={Kimberlyn Marie McGrail and Jennifer M. Phillips and Kathleen J Sweadner},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1991},
  volume={11 2},
  pages={381-91}
}
In the CNS, there are multiple isozymes of the sodium and potassium ion-stimulated adenosine triphosphatase (Na,K-ATPase) that have differences in affinity for Na+, ATP, and cardiac glycosides. Three forms of the catalytic subunit (designated alpha 1, alpha 2, and alpha 3) are known to be derived from different genes, but little is known of the cellular distributions of the proteins or their physiological roles. Isozyme-specific monoclonal antibodies permitted the immunofluorescent localization… CONTINUE READING
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