Immunofluorescent detection of CD15-fucosylated glycoconjugates in primary cerebellar cultures and their function in glial-neuronal adhesion in the central nervous system.

Expression of CD15 antigen (also referred to as stage specific embryonic antigen, SSEA-1, or Lewis(x)) was analyzed in cerebellar cultures prepared from seven day old rats by double immunostaining with anti-CD15 mAb7A and cell-specific antibodies to glial fibrillary acidic protein (GFAP) and Vimentin. The immunocytochemical data suggest that the expression… (More)