Immunoelectron-microscopic demonstration of NACP/alpha-synuclein-epitopes on the filamentous component of Lewy bodies in Parkinson's disease and in dementia with Lewy bodies.

@article{Arima1998ImmunoelectronmicroscopicDO,
  title={Immunoelectron-microscopic demonstration of NACP/alpha-synuclein-epitopes on the filamentous component of Lewy bodies in Parkinson's disease and in dementia with Lewy bodies.},
  author={Kunimasa Arima and Kenji Ueda and Nobuhiko Sunohara and Shunsaku Hirai and Yoko Izumiyama and Haruko Tonozuka-Uehara and Mitsuru Kawai},
  journal={Brain research},
  year={1998},
  volume={808 1},
  pages={93-100}
}
We examined brains from Parkinson's disease and from dementia with Lewy bodies (LBs) by using antibodies to NACP/alpha-synuclein. Immunohistochemically, all of the antibodies against the amino-terminal region, NAC domain, and carboxyl-terminal region of NACP labeled not only LBs, pale bodies (PBs), and dystrophic neurites, but also fine thread-like… CONTINUE READING