Immunodominance in the immune response to “multiple” histocompatibility antigens

  title={Immunodominance in the immune response to “multiple” histocompatibility antigens},
  author={Peter J. Wettstein and Donald W. Bailey},
Cytotoxic effector T cells putatively specific for multiple non-H-2 histocompatibility (H) antigens were generated by immunizing and boosting C57BL/6 and B6.C-H-2 dmice with BALB.B and BALB/c stimulator cells, respectively. The generated effectors were tested for cell-mediated lympholysis on a panel of targets whose BALB/c-derived non-H-2 H antigens were donated by CXB recombinant inbred mice. The spectrum of reactivity of cytotoxic effector T cells with CXB targets demonstrated that the… CONTINUE READING