Immunodetection of the metastasis-associated laminin receptor in human breast cancer cells obtained by fine-needle aspiration biopsy.

@article{Castronovo1990ImmunodetectionOT,
  title={Immunodetection of the metastasis-associated laminin receptor in human breast cancer cells obtained by fine-needle aspiration biopsy.},
  author={Vincent Castronovo and C. Colin and A P Claysmith and Paul H. Chen and Eric Lifrange and R. Lambotte and Henry C. Krutzsch and Lance A. Liotta and Mark E. Sobel},
  journal={The American journal of pathology},
  year={1990},
  volume={137 6},
  pages={1373-81}
}
Fine-needle aspiration biopsy of the breast is a very useful technique for the evaluation of a suspect lesion before surgical removal. Increased expression of the 67-kd laminin receptor has been associated with the metastatic phenotype of cancer cells, particularly in colon and breast cancers. In this study, the expression of laminin receptor was evaluated using the immunoperoxidase technique in 81 breast aspirates (26 benign and 55 neoplastic lesions). Cells obtained from benign samples… CONTINUE READING
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