Immunodepression following neurosurgical procedures.

  title={Immunodepression following neurosurgical procedures.},
  author={Khusru Asadullah and Christian Woiciechowsky and W D Doecke and Christa Liebenthal and Helmar Wauer and Wolfgang J. Kox and Hans Dieter Volk and Sonja Vogel and R von Baehr},
  journal={Critical care medicine},
  volume={23 12},
OBJECTIVE To determine the influence of a selective, sterile central nervous system surgery on immune reactivity, particularly whether a decrease of monocytic human leukocyte antigen-DR expression, indicating immunodepression, occurs after neurosurgery and if this measurement is useful for identification of patients with a high risk of infection. DESIGN Prospective study. SETTING Department of neurosurgery and intensive care unit in a university hospital. PATIENTS AND INTERVENTIONS Blood… CONTINUE READING