Immunodeficiencies in severe atopic dermatitis. Depressed chemotaxis and lymphocyte transformation.

@article{Rogge1976ImmunodeficienciesIS,
  title={Immunodeficiencies in severe atopic dermatitis. Depressed chemotaxis and lymphocyte transformation.},
  author={J L Rogge and Jon M. Hanifin},
  journal={Archives of dermatology},
  year={1976},
  volume={112 10},
  pages={
          1391-6
        }
}
Various reports have indicated assorted immune defects in atopic dermatitis, but the prevalence and degree of the defects remain unclear. We assessed various immunological factors in 14 patients with atopic dermatitis to determine whether immunodeficiencies were present consistently and were reflected by the patients' clinical characteristics. A high incidence of cutaneous infection was noted. Cutaneous delayed-hypersensitivity testing showed anergy in eight (67%) patients. Only the seven… CONTINUE READING
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