Immunocytological evidence for hematopoiesis in the early human placenta.

@article{Challier2005ImmunocytologicalEF,
  title={Immunocytological evidence for hematopoiesis in the early human placenta.},
  author={J. C. Challier and Mireille Galtier and Annie Cortez and T. Bintein and Mich{\`e}le Rabreau and Serge Uzan},
  journal={Placenta},
  year={2005},
  volume={26 4},
  pages={282-8}
}
Hematopoiesis has previously been observed in the human yolk sac, in placental villi and in the embryonic aorta. Here, our immunocytological study at 24 and 35 days showed packed erythroblasts in the placental vessels, mitotic figures and anti-Ki-67 reactions within these cells. Morphologically, the erythroblasts and vessels were similar to those found in the yolk sac during primitive hematopoiesis. In addition, numerous extravascular erythroblasts were found in the villous core. Positive… CONTINUE READING
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