Immunocytochemistry of sequence-related neuropeptides in Drosophila.

  title={Immunocytochemistry of sequence-related neuropeptides in Drosophila.},
  author={Michael F. Tibbetts and Ruthann Nichols},
  volume={24 6},
Based on structure, activity, and expression, the Drosophila drosulfakinin I peptide (DSK I; FDDY(OSO3H)GHMRFamide) is similar to the vertebrate peptide, cholecystokinin. Dromyosuppressin (DMS; TDVDHVFLRFamide) is an abundant peptide isolated from adult Drosophila which shares a high degree of sequence homology with peptides isolated from chicken, cockroach, fleshfly, and locust. DSK I and DMS, encoded by different precursors, have similar expression patterns in larval brain tissue; each… CONTINUE READING