Immunocytochemistry of neuron specific enolase (NSE) in the rat brain after single and repeated epileptic seizures.

Abstract

The aim of this study was to investigate neuron-specific enolase (NSE) immunoreactivity of the different brain regions after pentylenetetrazol (PTZ)- induced epileptic seizures in rats. Light microscopic examinations provided evidences for changes of neuronal activity after single and repeated seizures. The number of NSE (+) cells was well correlated with Nissl staining. The results suggest that NSE immunoreactivity may be a valuable marker for determination of the number of metabolically active neurons in different brain regions after single and repeated experimental seizures.

DOI: 10.1080/00207450701769232

Extracted Key Phrases

3 Figures and Tables

Cite this paper

@article{Yardimoglu2008ImmunocytochemistryON, title={Immunocytochemistry of neuron specific enolase (NSE) in the rat brain after single and repeated epileptic seizures.}, author={Melda Y Yardimoglu and Gul Ilbay and Cannur Dalçik and Hakki Dalçik and Deniz Sahin and Nurbay Ates}, journal={The International journal of neuroscience}, year={2008}, volume={118 7}, pages={981-93} }