Immunocytochemical study of transforming growth factor expression in benign and malignant gliomas.

@article{Samuels1989ImmunocytochemicalSO,
  title={Immunocytochemical study of transforming growth factor expression in benign and malignant gliomas.},
  author={V Samuels and Jeffrey M Barrett and S Bockman and Cooley G. Pantazis and Marshall B. Allen},
  journal={The American journal of pathology},
  year={1989},
  volume={134 4},
  pages={894-902}
}
Immunocytochemical studies using polyclonal antibodies to epidermal growth factor (EGF) and transforming growth factor (TGF) alpha and beta were performed on 20 cases of human gliomas. EGF immunoreactive material was detected in both benign and malignant glial tumors. In addition, EGF immunoreactive material was detected in normal brain. TGF-beta was detected in both benign and malignant tumors, but was not detected in normal brain. In contrast, TGF-alpha was highly conserved in its expression… CONTINUE READING

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