Immunocytochemical studies of the interactions of cadherins and catenins in the early Xenopus embryo.

@article{Kurth1999ImmunocytochemicalSO,
  title={Immunocytochemical studies of the interactions of cadherins and catenins in the early Xenopus embryo.},
  author={Thomas Kurth and I V Fesenko and Sylke Schneider and Frank E. M{\"u}nchberg and Thomas O. Joos and Thomas P. Spieker and Peter Hausen},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={1999},
  volume={215 2},
  pages={155-69}
}
Linkage of cadherins to the cytoskeleton is crucial for their adhesive function. Since alpha- and beta-catenin play a key role in this linkage, these proteins are possible targets for processes that control cell-cell adhesion. To achieve a better understanding of the regulation of cell-cell adhesion in embryonic morphogenesis, we used immunohistology to investigate how in Xenopus blastomeres catenins respond to disturbances in the expression of maternal cadherins. Overexpression of myc-tagged… CONTINUE READING
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