Immunocytochemical studies in the ceroid-lipofuscinoses (Batten disease) using antibodies to subunit c of mitochondrial ATP synthase.

@article{Westlake1995ImmunocytochemicalSI,
  title={Immunocytochemical studies in the ceroid-lipofuscinoses (Batten disease) using antibodies to subunit c of mitochondrial ATP synthase.},
  author={Valerie J Westlake and Robert D. Jolly and S. L. Bayliss and David N Palmer},
  journal={American journal of medical genetics},
  year={1995},
  volume={57 2},
  pages={177-81}
}
Immunocytochemistry, using antibodies against subunit c of mitochondrial ATP synthase, has been carried out in the ovine, canine, late infantile, and adult forms of ceroid-lipofuscinosis. Intensity of staining varied depending on the particular disease, species, fixation regime, and the antibody used. Differential staining of storage cytosomes in neurons of affected sheep and those in the late infantile patient suggested exposure of different epitopes. This was supported by the variable… CONTINUE READING

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