Immunocytochemical localization of the alpha 1 and beta 2/3 subunits of the GABAA receptor in relation to specific GABAergic synapses in the dentate gyrus.

@article{Nusser1995ImmunocytochemicalLO,
  title={Immunocytochemical localization of the alpha 1 and beta 2/3 subunits of the GABAA receptor in relation to specific GABAergic synapses in the dentate gyrus.},
  author={Zoltan Nusser and J. David B. Roberts and Agn{\'e}s Baude and J. Grayson Richards and Werner Sieghart and Peter Somogyi},
  journal={The European journal of neuroscience},
  year={1995},
  volume={7 4},
  pages={630-46}
}
Dentate granule cells receive spatially segregated GABAergic innervation from at least five types of local circuit neurons, and express mRNA for at least 11 subunits of the GABAA receptor. At most two to four different subunits are required to make a functional pentamer, raising the possibility that cells have on their surface several types of GABAA receptor channel, which may not be uniformly distributed. In order to establish the subcellular location of GABAA receptors on different parts of… CONTINUE READING