Immunocytochemical localization of a gastric imhibitory polypeptide-like material within A-cells of the endocrine pancreas.

@article{Smith1977ImmunocytochemicalLO,
  title={Immunocytochemical localization of a gastric imhibitory polypeptide-like material within A-cells of the endocrine pancreas.},
  author={Philip W. Smith and F W Merchant and David G. Johnson and Wilfred Y. Fujimoto and Robert H. Williams},
  journal={The American journal of anatomy},
  year={1977},
  volume={149 4},
  pages={585-90}
}
In rat pancreatic islets, the glucagon-producing A-cells also contain a GIP-like material as revealed by the peroxidase-antiperoxidase immunocytochemical technique. Control studies showed that this dual staining was not due to the cross-reactivity of anti-GIP with glucagon. It is concluded either that the A-cells synthesize a GIP-like peptide or that it is taken up from the circulation. 

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