Immunocytochemical investigation of insulin secretion by pancreatic beta-cells in control and diabetic Psammomys obesus.

@article{Bendayan1995ImmunocytochemicalIO,
  title={Immunocytochemical investigation of insulin secretion by pancreatic beta-cells in control and diabetic Psammomys obesus.},
  author={Mo{\"i}se Bendayan and Daniela Malide and Ehud Ziv and Emile Levy and ResolutionEli Ben-Sasson and Rony Kalman and H Bar-on and Michel Chr{\'e}tien and Nabil G. Seidah},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={1995},
  volume={43 8},
  pages={771-84}
}
Hyperproinsulinemia is a characteristic feature of non-insulin-dependent diabetes mellitus (NIDDM) caused by pancreatic beta-cell dysfunction through a secretion-related alteration or impaired proinsulin processing. We have investigated the insulin processing and secretion in Psammomys obesus fed with low- and high-energy diets, which represent a model for… CONTINUE READING