Immunocytochemical evidence for differential subcellular localization of 5 alpha-reductase isoenzymes in human tissues.

@article{Aumller1996ImmunocytochemicalEF,
  title={Immunocytochemical evidence for differential subcellular localization of 5 alpha-reductase isoenzymes in human tissues.},
  author={Gerhard Aum{\"u}ller and Wolfgang Eicheler and Heiner Renneberg and Knut Adermann and Pekka Vilja and Wolf Georg Forssmann},
  journal={Acta anatomica},
  year={1996},
  volume={156 4},
  pages={241-52}
}
To contrast the previously described distribution of 5 alpha-reductase isoenzyme 2 in human organs we have raised synthetic C-terminal peptides of human 5 alpha-reductase isoenzyme 1 (h 5 alpha r1) and isoenzyme 2 (h 5 alpha r2) respectively, and studied the cellular and subcellular distribution of both isoforms of this key enzyme of testosterone metabolism using the human prostate gland as a reference. h 5 alpha r1, which in Western blots of human prostatic proteins had an apparent molecular… CONTINUE READING
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