Immunocytochemical detection of ERG expression in exfoliated urinary cells identifies with high specificity patients with prostate cancer.

@article{Pal2016ImmunocytochemicalDO,
  title={Immunocytochemical detection of ERG expression in exfoliated urinary cells identifies with high specificity patients with prostate cancer.},
  author={Raj P. Pal and Roger Clive Kockelbergh and John Howard Pringle and Lara Cresswell and Roger Hew and John P. Dormer and Colin S Cooper and John Kilian Mellon and Julian G Barwell and Edward J. Hollox},
  journal={BJU international},
  year={2016},
  volume={117 4},
  pages={686-96}
}
OBJECTIVES To evaluate the immunocytochemical detection of ERG protein in exfoliated cells as a means of identifying patients with prostate cancer (PCa) before prostate biopsy. MATERIALS AND METHODS Urine samples (30 mL) were collected after digital rectal examination (DRE) from 159 patients with an elevated age-specific prostate-specific antigen (PSA) and/or an abnormal DRE who underwent prostate biopsy. In all cases, exfoliated urinary cells from half of the urine sample underwent… CONTINUE READING

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