Immunocytochemical detection of 14-3-3 in primary nervous system tumors

@article{Cao2005ImmunocytochemicalDO,
  title={Immunocytochemical detection of 14-3-3 in primary nervous system tumors},
  author={Wei-dong Cao and Xiang Zhang and Jianning Zhang and Zhijun Yang and Hai-ning Zhen and Guang Cheng and Bian Li and Dakuan Gao},
  journal={Journal of Neuro-Oncology},
  year={2005},
  volume={77},
  pages={125-130}
}
14-3-3 proteins have attracted much recent interest in the etiopathogenesis of human cancers owing to their involvement in the prevention of apoptosis. However, the expression of 14-3-3 in primary nervous system tumors has not been previously characterized. In this paper, Immunohistochemistry using a specific anti-14-3-3 antibody was performed on formalin-fixed, paraffin embedded archival tissue from 124 primary human nervous system tumors and 10 normal brain tissues. In the normal control… CONTINUE READING