Immunocytochemical demonstration of nerve growth factor (NGF) receptor in the pineal gland: effect of NGF on pinealocyte neurite formation.

Abstract

Nerve growth factor receptor immunoreactivity (NGFRI) in the pineal gland was examined both light and electron microscopically using the monoclonal antibody 192IgG. NGFRI was located on sympathetic fibers and on perivascular cells resembling macrophage/microglia. A pineal gland dispersed cell culture model confirmed the presence of NGFRI in cells that… (More)

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