Immunocytochemical analysis of gangliosides in rat primary cerebellar cultures using specific monoclonal antibodies.

Abstract

We studied the expression of ganglioside antigens in primary cultures of rat cerebellum using an immunocytochemical technique with mouse monoclonal antibodies (MAbs) specific for various gangliosides. Twelve MAbs that specifically recognize each ganglioside were used. Our study revealed that there is a cell type-specific expression of ganglioside antigens… (More)

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