Immunocontraceptive properties of recombinant sperm protein DE: implications for the development of novel contraceptives.

Abstract

OBJECTIVE To evaluate the immunocontraceptive properties of recombinant DE, a sperm epididymal protein involved in fertilization, via an experimental study in rats as a critical step toward the development of a human immunocontraceptive. DESIGN In vivo study in rats. SETTING Animal care facility of an academic research center. ANIMAL(S) Seventy-four… (More)

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