Immunocontraceptive potential of major antigenic determinants of chicken riboflavin carrier protein in the female rat.

@article{Subramanian2000ImmunocontraceptivePO,
  title={Immunocontraceptive potential of major antigenic determinants of chicken riboflavin carrier protein in the female rat.},
  author={Sarada Subramanian and A A Karande and P. Radhakantha Adiga},
  journal={Vaccine},
  year={2000},
  volume={19 9-10},
  pages={1172-9}
}
Earlier investigations have demonstrated that antibodies generated against the N-terminal (10-17) and C-terminal (200-207) ends of chicken riboflavin carrier protein (RCP; 219 AA), but not towards the internal region (172-179), curtail pregnancy establishment in rodents and sub-human primates. In those studies, epitope peptides conjugated to diphtheria toxoid were used as immunogens. In the present study, linkage of these sequences to extraneous carriers was avoided to rule out the possibility… CONTINUE READING