Immunocontraception with zona pellucida proteins.

  title={Immunocontraception with zona pellucida proteins.},
  author={Margaret Paterson and Zo{\"e} A Jennings and Marcel van Duin and Robert John Aitken},
  journal={Cells, tissues, organs},
  volume={166 2},
The prospect of an immunological approach to contraception that would disrupt the process of fertilisation itself has resulted in a considerable interest into research in this area. It has been known for some time that antibodies raised against the zona pellucida (ZP) can suppress fertility very effectively. However, the initial optimism of this approach has been marred by the appearance of an ovarian pathology characterised by disruption of folliculogenesis and depletion of the primordial… CONTINUE READING