Immunochemical study of a human myeloma IgG1 half molecule.


The serum of a patient with multiple myeloma contained an IgG1 kappa monoclonal protein which existed in two molecular species: one with and one without inter-heavy chain covalent bonds, the latter dissociating into half molecules without reduction. The half molecules were present in the urine together with a kappa Bence-Jones protein. This peculiar protein… (More)


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@article{Seligmann1978ImmunochemicalSO, title={Immunochemical study of a human myeloma IgG1 half molecule.}, author={Maxime Seligmann and Edith Mihaesco and Aaron Chevalier and Roger Miglierina}, journal={Annales d'immunologie}, year={1978}, volume={129 C 6}, pages={855-70} }