Immunochemical structure of hepatitis B e antigen in the serum.

  title={Immunochemical structure of hepatitis B e antigen in the serum.},
  author={Kazuaki Takahashi and Atsuhiko Machida and Gunki Funatsu and Masayasu Nomura and Sadakazu Usuda and Satoka Aoyagi and Kuniomi Tachibana and Hironobu Miyamoto and Mitsunobu Imai and Takao Nakamura and Yuzo Miyakawa and Makoto Mayumi},
  journal={Journal of immunology},
  volume={130 6},
Hepatitis B e antigen (HBeAg) constitutes the nucleocapsid of hepatitis B virus (HBV) and occurs in association with plasma proteins, particularly with IgG, in the serum of persons infected with the virus. A polypeptide with an approximate m.w. of 15,500 (P15.5) is obtained either from HBeAg in the serum or from the nucleocapsid of HBV. P15.5 preparations from serum and virus resembled closely each other in the amino acid composition. The C-terminus amino acid sequence of P15.5 from serum was… CONTINUE READING
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