Immunochemical relationship between Forssman and globoside glycolipid antigens.

  title={Immunochemical relationship between Forssman and globoside glycolipid antigens.},
  author={Robin A. Karol and Smriti K. Kundu and Donald M. Marcus},
  journal={Immunological communications},
  volume={10 3},
The rabbit antibody response to the human blood group P glycolipid antigen, globoside, GalNAc(beta 1-3)Gal(alpha 1-4)Gal(beta 1-4)Glc-Cer, has been examined with respect to cross-reactions with the structurally related Forssman glycolipid GalNAc(alpha 1-3)GalNAc(beta 1-3)Gal(alpha 1-4)Gal(beta 1-4)Glc-Cer. Immunoadsorbent columns were used to isolate three purified antibody populations from the anti-globoside sera: (1) fraction A, antibodies that cross-react with both glycolipids; (2) fraction… CONTINUE READING