Immunochemical quantification of Cu/Zn superoxide dismutase in prenatal diagnosis of Down's syndrome

@article{Porstmann1990ImmunochemicalQO,
  title={Immunochemical quantification of Cu/Zn superoxide dismutase in prenatal diagnosis of Down's syndrome},
  author={Tomas Porstmann and Roselotte Wietschke and G{\"u}nther Cobet and Katja Lorenz and Roland Grunow and S. A. A. Jahn and Rainer Bollmann and Gudrun Stamminger and R{\"u}diger von Baehr},
  journal={Human Genetics},
  year={1990},
  volume={85},
  pages={362-366}
}
Cu/Zn Superoxide dismutase (SOD) was quantified by enzyme immunoassay for prenatal diagnosis of Down's syndrome. Overall, 154 samples of amniotic fluid, 72 samples of amniotic cells and 31 samples of chorionic tissue were investigated. Due to the large biological variance of the SOD concentrations in normal pregnancies (range for amniotic fluid 10.5–154.9, for amniotic cells 40.0–338.8, and for chorionic tissue 132.2–649.5 g SOD/g protein) the cases of Down's syndrome detected by karyotype… CONTINUE READING
1 Extracted Citations
24 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 24 references

Human genetics - problems and approaches, 2nd edn

  • F Vogel, AG Motulsky
  • 1986
1 Excerpt

Similar Papers

Loading similar papers…