Immunochemical detection of oxidatively damaged DNA

@article{Rossner2012ImmunochemicalDO,
  title={Immunochemical detection of oxidatively damaged DNA},
  author={P. Rossner and R. Sram},
  journal={Free Radical Research},
  year={2012},
  volume={46},
  pages={492 - 522}
}
  • P. Rossner, R. Sram
  • Published 2012
  • Medicine, Chemistry
  • Free Radical Research
  • Abstract Oxidatively damaged DNA is implicated in various diseases, including neurodegenerative disorders, cancer, diabetes, cardiovascular and inflammatory diseases as well as aging. Several methods have been developed to detect oxidatively damaged DNA. They include chromatographic techniques, the Comet assay, 32P-postlabelling and immunochemical methods that use antibodies to detect oxidized lesions. In this review, we discuss the detection of 8-oxo-7,8-dihydro-29-deoxyguanosine (8-oxodG… CONTINUE READING
    30 Citations
    Special issue on DNA oxidation: Mechanisms, measurement and consequences
    • M. Cooke
    • Chemistry, Medicine
    • Free radical research
    • 2012
    • 5
    An automated Fpg-based FADU method for the detection of oxidative DNA lesions and screening of antioxidants.
    • 8
    • PDF
    Oxidative DNA damages by chemical exposures at work
    • 2
    • PDF
    Oxidative stress and inflammation generated DNA damage by exposure to air pollution particles.
    • 164
    Free radical and superoxide reactivity detection in semen quality assessment: past, present, and future
    • 29
    • PDF

    References

    SHOWING 1-10 OF 275 REFERENCES
    DNA Damage, a Biomarker of Carcinogenesis: Its Measurement and Modulation by Diet and Environment
    • E. Hwang, P. Bowen
    • Chemistry, Medicine
    • Critical reviews in food science and nutrition
    • 2007
    • 79
    Oxidative DNA damage and disease: induction, repair and significance.
    • 1,078
    Ameliorating effect of N-acetylcysteine and curcumin on pesticide-induced oxidative DNA damage in human peripheral blood mononuclear cells
    • 29
    • PDF
    Measurement and Meaning of Oxidatively Modified DNA Lesions in Urine
    • 188
    • PDF
    Isocyanates induces DNA damage, apoptosis, oxidative stress, and inflammation in cultured human lymphocytes
    • 54
    High DNA Oxidative Damage in Systemic Sclerosis
    • 50
    8-hydroxy-2′ -deoxyguanosine (8-OHdG): A Critical Biomarker of Oxidative Stress and Carcinogenesis
    • 1,091
    • PDF
    In situ detection of oxidative DNA damage, 8-hydroxydeoxyguanosine, in chronic human liver disease.
    • 93