Immunochemical characterization of the Ly-8.2 murine lymphocyte alloantigen: possible relationship to actin.

Abstract

An immunochemical analysis of the Ly-8.2 antigen was performed. Reactivity of B10-radiolabeled T and B cell lysates with a C3H anti-AKR serum immunoprecipitates a major 43,000 m.w. protein detectable by one-dimensional gel electrophoresis. The protein can be radioiodinated, however, it does not appear to blind to lentil lectin. Two-dimensional gel electro phoresis and peptide-mapping studies indicate that this protein is structurally very similar to lymphocyte actin. The possible molecular relationship between Ly-8.2, other lymphocyte membrane antigens, and actin is discussed.

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@article{Delovitch1979ImmunochemicalCO, title={Immunochemical characterization of the Ly-8.2 murine lymphocyte alloantigen: possible relationship to actin.}, author={Terry L . Delovitch and A Fegelman and Brian H. Barber and Jeffrey Frelinger}, journal={Journal of immunology}, year={1979}, volume={122 1}, pages={326-33} }