Immunochemical characterization of alpha-bungarotoxin detoxified with glutaraldehyde.

Abstract

Modification of alpha-bungarotoxin (alpha-BuTX) with glutaraldehyde (GA), a bifunctional reagent, resulted in the formation of crosslinked derivatives. The intramolecular linked monomeric derivative as well as dimeric and higher molecular weight derivatives arising from intermolecular reactions were separated by gel filtration. The dimer and polymers were… (More)

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