Immunochemical Determination of Pyocyanin and 1-Hydroxyphenazine as Potential Biomarkers of Pseudomonas aeruginosa Infections.

@article{Pastells2016ImmunochemicalDO,
  title={Immunochemical Determination of Pyocyanin and 1-Hydroxyphenazine as Potential Biomarkers of Pseudomonas aeruginosa Infections.},
  author={Carme Pastells and Nuria Pascual and Francisco S{\'a}nchez-Baeza and M-Pilar Marco},
  journal={Analytical chemistry},
  year={2016},
  volume={88 3},
  pages={1631-8}
}
A novel immunochemical approach to diagnose Pseudomonas aeruginosa infections is reported, which is based on the quantification of relevant and specific virulence factors secreted by this microorganism. Specific antibodies have been raised using hapten PC1 (a 1:1 mixture of 9-hydroxy- and 6-hydroxy-phenazine-2-carobxylic acids), designed to recognize 1… CONTINUE READING